Implicit neural representations (INRs) have demonstrated success in a variety of applications, including inverse problems and neural rendering. An INR is typically trained to capture one signal of interest, resulting in learned neural features that are highly attuned to that signal. Assumed to be less generalizable, we explore the aspect of transferability of such learned neural features for fitting similar signals.

Clinical diagnosis of the eye is performed over multifarious data modalities including scalar clinical labels, vectorized biomarkers, two-dimensional fundus images, and three-dimensional Optical Coherence Tomography (OCT) scans. Clinical practitioners use all available data modalities for diagnosing and treating eye diseases like Diabetic Retinopathy (DR) or Diabetic Macular Edema (DME). Enabling usage of machine learning algorithms within the ophthalmic medical domain requires research into the relationships and interactions between all relevant data over a treatment period. Existing datasets are limited in that they neither provide data nor consider the explicit relationship modeling between the data modalities. In this paper, we introduce the Ophthalmic Labels for Investigating Visual Eye Semantics (OLIVES) dataset that addresses the above limitation. This is the first OCT and near-IR fundus dataset that includes clinical labels, biomarker labels, disease labels, and time-series patient treatment information from associated clinical trials. The dataset consists of 1268 near-IR fundus images each with at least 49 OCT scans, and 16 biomarkers, along with 4 clinical labels and a disease diagnosis of DR or DME. In total, there are 96 eyes' data averaged over a period of at least two years with each eye treated for an average of 66 weeks and 7 injections. We benchmark the utility of OLIVES dataset for ophthalmic data as well as provide benchmarks and concrete research directions for core and emerging machine learning paradigms within medical image analysis.

A prevailing belief in attack and defense community is that the higher flatness of adversarial examples enables their better cross-model transferability, leading to a growing interest in employing sharpness-aware minimization and its variants. However, the theoretical relationship between the transferability of adversarial examples and their flatness has not been well established, making the belief questionable. To bridge this gap, we embark on a theoretical investigation and, for the first time, derive a theoretical bound for the transferability of adversarial examples with few practical assumptions. Our analysis challenges this belief by demonstrating that the increased flatness of adversarial examples does not necessarily guarantee improved transferability. Moreover, building upon the theoretical analysis, we propose TPA, a Theoretically Provable Attack that optimizes a surrogate of the derived bound to craft adversarial examples. Extensive experiments across widely used benchmark datasets and various real-world applications show that TPA can craft more transferable adversarial examples compared to state-of-the-art baselines. We hope that these results can recalibrate preconceived impressions within the community and facilitate the development of stronger adversarial attack and defense mechanisms. The source codes are available in https://github.com/fmy266/TPA.

This method classifies an image by comparing it to a set of learned prototypes, providing explanations of the form "this looks like that." In our model, a prototype consists of parts, which can deform over irregular geometries to create a better comparison between images. Unlike existing models that rely on Convolutional Neural Network (CNN) backbones and spatially rigid prototypes, our model integrates Vision Transformer (ViT) backbones into prototype based models, while offering spatially deformed prototypes that not only accommodate geometric variations of objects but also provide coherent and clear prototypical feature representations with an adaptive number of prototypical parts. Our experiments show that our model can generally achieve higher performance than the existing prototype based models. Our comprehensive analyses ensure that the prototypes are consistent and the interpretations are faithful. Our code is available at https://github.com/Henrymachiyu/ProtoViT.

In this work, we introduce Pixelsmith, a zero-shot text-to-image generative framework to sample images at higher-resolutions with a single GPU. We are the first to show that it is possible to scale the output of a pre-trained diffusion model by a factor of 1000, opening the road for gigapixel image generation at no additional cost. Our cascading method uses the image generated at the lowest resolution as a baseline to sample at higher-resolutions. For the guidance, we introduce the Slider, a tunable mechanism that fuses the overall structure contained in the first-generated image with enhanced fine details. At each inference step, we denoise patches rather than the entire latent space, minimizing memory demands such that a single GPU can handle the process, regardless of the image's resolution. Our experimental results show that Pixelsmith not only achieves higher quality and diversity compared to existing techniques, but also reduces sampling time and artifacts.

Large Multimodal Models (LMMs) have shown remarkable capabilities across a variety of tasks (e.g., image captioning, visual question answering). While broad, their knowledge remains generic (e.g., recognizing a dog), and they are unable to handle personalized subjects (e.g., recognizing a user's pet dog). Human reasoning, in contrast, typically operates within the context of specific subjects in our surroundings. For example, one might ask, "What should I buy for my dog's birthday?";

Knowledge transfer between multi-omic single-cell data aims to effectively transfer cell types from scRNA-seq data to unannotated scATAC-seq data. Several approaches aim to reduce the heterogeneity of multi-omic data while maintaining the discriminability of cell types with extensive annotated data. However, in reality, the cost of collecting both a large amount of labeled scRNA-seq data and scATAC-seq data is expensive. Therefore, this paper explores a practical yet underexplored problem of knowledge transfer across multi-omic single-cell data under cell type scarcity. To address this problem, we propose a semi-supervised knowledge transfer framework named Dual label scArcity elimiNation with Cross-omic multi-samplE Mixup (DANCE). To overcome the label scarcity in scRNA-seq data, we generate pseudo-labels based on optimal transport and merge them into the labeled scRNAseq data.

A.1 Network Architecture Our encoder-decoder architecture for a 3D input is shown in Fig. A.1. The architecture for a 2D input is the same, only using 2D convolutions and a 2D attribute space. The key components of the attribute encoder include using down ResNet blocks (with average pooling, and leaky ReLU activation) for encoding the input image into a relatively large 3D latent space of size 8 10 8 (in the 3D case), as opposed to a 1D vector, which is commonly seen in Variational Autoencoders (VAEs). We also added a fully connected layer to the attribute latent space to enable classification. In early development, we found that using a 1D vector in the latent space was insufficient for encoding the required class information for brain imaging, and observed that some class information was instead encoded in the content encoder, which is meant to be class invariant.

Reconstructing and understanding 3D structures from a limited number of images is a classical problem in computer vision.

Precise and accurate predictions over boundary areas are essential for semantic segmentation. However, the commonly-used convolutional operators tend to smooth and blur local detail cues, making it difficult for deep models to generate accurate boundary predictions. In this paper, we introduce an operator-level approach to enhance semantic boundary awareness, so as to improve the prediction of the deep semantic segmentation model. Specifically, we first formulate the boundary feature enhancement as an anisotropic diffusion process. We then propose a novel learnable approach called semantic diffusion network (SDN) to approximate the diffusion process, which contains a parameterized semantic difference convolution operator followed by a feature fusion module. Our SDN aims to construct a differentiable mapping from the original feature to the inter-class boundary-enhanced feature. The proposed SDN is an efficient and flexible module that can be easily plugged into existing encoder-decoder segmentation models. Extensive experiments show that our approach can achieve consistent improvements over several typical and state-of-the-art segmentation baseline models on challenging public benchmarks.